Type of Cancer Hodgkin's and non-Hodgkin's lymphoma, multiple myeloma, sarcomas, leukemias, neuroblastoma, breast, lung, testis, endometrium, mycosis fungoides 
Route Administered Oral, Intravenous 
Precautions Increased fluid intake, bladder emptying 
Side Effects Hair loss, bladder irritation or hemorrhage, anemia, low blood counts, immunosuppression, water overload (antidiuretic effect), sterility, lung scarring, increased skin pigmentation, loss of appetite, nausea, vomiting, sore mouth (stomatitis), diarrhea, gastrointestinal ulcers, increased uric acid (gout), secondary malignancies